Phospho-NuMA (Ser395) Rabbit Polyclonal Antibody
No Size Price Availability  
YRP03317P-01 50ul 1500.00 In Stock
YRP03317P-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 4926
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
NuMA (Nuclear Mitotic Apparatus Protein) is an intranuclear protein and present in nucleus during interphase. At the onset of mitosis, it redistributes from the nucleus to two centrosomal structures that later will become part of the mitotic spindle pole. After anaphase, the protein redistributes from the spindle polar region into reforming nucleus. NuMA is an essential protein during mitosis for the terminal phases of chromosome separation and/or nuclear reassembly. Recently a study shows that NuMA is cleaved to a 180 to 200kDa during apoptosis.
Reactivity Human
Tested applications IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic phosphopeptide derived from human NuMA around the phosphorylation site of Ser395
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym NUMA 1, NuMA protein, NUMA1, SP H antigen, Structural nuclear protein, Centrophilin stabilizes mitotic spindle in mitotic cells, Nuclear mitotic apparatus protein 1, Nuclear mitotic apparatus protein.
This product is for research use only, not for diagnostic or therapeutic use!

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