| No | Size | Price | Availability | |
| YRP03179P-01 | 50ul | 1500.00 | In Stock |  |
| YRP03179P-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 8841 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]. |
| Reactivity | Human, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human HDAC3 around the phosphorylation site of Ser424 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | HDAC3 phospho S424, HDAC3 phospho Ser424, p-HDAC3 Ser424, RPD3 2, RPD3-2, HD 3, HD3, HDAC 3, Histone deacetylase 3 HD3 RPD3-2, histone deacetylase 3, RPD 3, RPD3, SMAP 45, SMAP-45, SMAP45, HDAC3_HUMAN. |
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