| No | Size | Price | Availability | |
| YRP03125P-01 | 50ul | 1500.00 | In Stock |  |
| YRP03125P-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 898 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers. |
| Reactivity | Human |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human Cyclin E around the phosphorylation site of Thr395 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | Cyclin E1 phospho T395, p-Cyclin E1 phospho T395, Cyclin E1 Thr395, CCNE 1, CCNE;CCNE1;Cyclin E1 antibody Cyclin Es;Cyclin Et;CyclinE, G1/S specic cyclin E, CCNE1_HUMAN. |
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