

| Source: | Rabbit | Gene Id: | 3949 |
| Isotype: | IgG | Swiss Prot: | P01130 |
| purity: | Purified by Protein A. |
| Background: |
| Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells. |
| Reactivity | Human, Mouse, Other Species (Hamster) |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human LDL-R |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | FH, FHC, LDLCQ2, Low-density lipoprotein receptor, LDL receptor, LDLR |
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