Bcr Rabbit Polyclonal Antibody
No Size Price Availability  
YRP02752-01 50ul 1500.00 In Stock
YRP02752-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 613
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human Bcr
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym ALL, BCR 1, BCR/ABL FUSION GENE INCLUDED, BCR/FGFR1 FUSION GENE INCLUDED, BCR/PDGFRA FUSION GENE INCLUDED, BCR1, breakpoint cluster region, CML, PHL, BCR_HUMAN.
This product is for research use only, not for diagnostic or therapeutic use!

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