Cathepsin C/DPP1 Rabbit Polyclonal Antibody
No Size Price Availability  
YRP02677-01 50ul 1500.00 In Stock
YRP02677-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 1075
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human DPP-I
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym Dipeptidyl peptidase I, AI047818, CATC, Cathepsin C, Cathepsin J, CPPI, CTSC, Dipeptidyl peptidase 1, Dipeptidyl transferase, DPP I, DPPI, EC 3.4.14.1, HMS, JP, JPD, MGC126959, PALS, PLS.
This product is for research use only, not for diagnostic or therapeutic use!

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