Langerin/CD207 Rabbit Polyclonal Antibody
No Size Price Availability  
YRP02655-01 50ul 1500.00 In Stock
YRP02655-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 50489
Isotype: IgG Swiss Prot: Q9UJ71
purity: Purified by Protein A.
Background:
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human CD207
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym CLEC4K, C-type lectin domain family 4 member K, Langerin, CD207
This product is for research use only, not for diagnostic or therapeutic use!

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