Integrin alpha 2bPolyclonal Rabbit Polyclonal Antibody
No Size Price Availability  
YRP02641-01 50ul 1500.00 In Stock
YRP02641-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 16399
Isotype: IgG Swiss Prot: Q9QUM0
purity: Purified by Protein A.
Background:
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Reactivity Human, Mouse, Rat
Tested applications IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from mouse Integrin alpha 2b
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym CD41, CD41B, GpIIb, AI172977, alphaIIb, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, Itga2b
This product is for research use only, not for diagnostic or therapeutic use!

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