Source: | Rabbit | Gene Id: | 25402 |
Isotype: | IgG | Swiss Prot: | P55213 |
purity: | Purified by Protein A. |
Background: |
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from rat Caspase 3 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | Lice, Caspase-3, CASP-3, Apopain, Cysteine protease CPP32, CPP-32, IRP, Protein Yama, SREBP cleavage activity 1, SCA-1, Casp3, Cpp32 |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.