| No | Size | Price | Availability | |
| YRP00682-01 | 50ul | 1500.00 | In Stock |  |
| YRP00682-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 285 |
| Isotype: | IgG | Swiss Prot: | O15123 |
| purity: | Purified by Protein A. |
| Background: |
| Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. |
| Reactivity | Human, Mouse, Rat, Pig |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human Angiopoietin 2 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | ANG2, AGPT2, Angiopoietin-2, ANG-2, ANGPT2 |
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