Phospho-PKC beta 1/2 (Thr500) Rabbit Polyclonal Antibody
No Size Price Availability  
YRP02510P-01 50ul 1500.00 In Stock
YRP02510P-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5579
Isotype: IgG Swiss Prot: P05771
purity: Purified by Protein A.
Background:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human PRKCB around the phosphorylation site of Thr500
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym PKCB, PRKCB1, PRKCB2, PKC-beta, Protein kinase C beta type, PKC-B, PRKCB
This product is for research use only, not for diagnostic or therapeutic use!

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