Source: | Rabbit | Gene Id: | 4325 |
Isotype: | IgG | Swiss Prot: | P51512 |
purity: | Purified by Protein A. |
Background: |
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB FC IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
FC 1:20-1:100
|
Immunogen | KLH conjugated synthetic peptide derived from human MMP-16 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | MMP-X2, C8orf57, MT-MMP2, MT-MMP3, MT3-MMP, Matrix metalloproteinase-16, MMP-16, Membrane-type matrix metalloproteinase 3, MT-MMP 3, MTMMP3, Membrane-type-3 matrix metalloproteinase, MT3MMP, MMP16, MMPX2 |
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