FDC-SP Rabbit Polyclonal Antibody
No Size Price Availability  
YRP01771-01 50ul 1500.00 In Stock
YRP01771-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 494224
Isotype: IgG Swiss Prot: Q5R1M6
purity: Purified by Protein A.
Background:
Follicular dendritic cells are cells that facilitate antigen recognition by B cells in follicles. This kind of dendritic cell is not bone marrow derived and is not a kind of blood cell. It is purely a resident of the follicles of secondary lymphoid organs. B cells form germinal centers around follicular dendritic cells in lymphoid organs. Dendritic cells form from monocytes, white blood cells which circulate in the body and, depending on the right signal, can turn into dendritic cells or macrophages. The monocytes in turn are formed from stem cells in the bone marrow.In normal tissue this antibody identifies dendritic cells and a proportion of B lymphocytes. Evidence in pathological tissue and functional studies suggests it binds to an epitope expressed by antigen presenting cells. Within the macrophage/dendritic cell populations the epitope seen by RFD1 is coexpressed with RFD7 by a subset of cells that exhibit suppressive activity on T cell stimulation.
Reactivity Human, Mouse, Rat
Tested applications IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from rat FDC-SP
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym FDC, FDCs, Follicular dendritic cell, Follicular dendritic cell secreted protein, Follicular dendritic cell, Follicular dendritic cell secreted peptide, FDC secreted protein.
This product is for research use only, not for diagnostic or therapeutic use!

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