PKA alpha + beta Rabbit Polyclonal Antibody
No Size Price Availability  
YRP00525-01 50ul 1500.00 In Stock
YRP00525-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 282323
Isotype: IgG Swiss Prot: P05131
purity: Purified by Protein A.
Background:
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, and differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis (By similarity).
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from bovine PKA
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym cAMP-dependent protein kinase catalytic subunit beta, PKA C-beta, PRKACB
This product is for research use only, not for diagnostic or therapeutic use!

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