| No | Size | Price | Availability | |
| YRP14104-01 | 50ul | 1500.00 | In Stock |  |
| YRP14104-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 10106 |
| Isotype: | IgG | Swiss Prot: | O14595 |
| purity: | Purified by Protein A. |
| Background: |
| Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human CTDSP2 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | OS4, PSR2, SCP2, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2, Nuclear LIM interactor-interacting factor 2, NLI-interacting factor 2, Protein OS-4, Small C-terminal domain phosphatase 2, Small CTD phosphatase 2, CTDSP2, NIF2 |
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