| No | Size | Price | Availability | |
| YRP13646-01 | 50ul | 1500.00 | In Stock |  |
| YRP13646-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2888 |
| Isotype: | IgG | Swiss Prot: | Q14449 |
| purity: | Purified by Protein A. |
| Background: |
| Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human GRB 14 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | Growth factor receptor-bound protein 14, GRB14 adapter protein, GRB14 |
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