| No | Size | Price | Availability | |
| YRP13399-01 | 50ul | 1500.00 | In Stock |  |
| YRP13399-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 51022 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB FC IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
FC 1:20-1:100
|
| Immunogen | KLH conjugated synthetic peptide derived from human Glutaredoxin 2 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | bA101E13.1 GRX2 glutaredoxin thioltransferase 2, bA101E13.1, CGI133, Glrx2, GLRX2_HUMAN, Glutaredoxin-2, Glutaredoxin-2, mitochondrial, GRX2, mitochondrial. |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
