GBA3/CBG Rabbit Polyclonal Antibody
No Size Price Availability  
YRP13303-01 50ul 1500.00 In Stock
YRP13303-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 57733
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
CBG is a monomeric enzyme involved in the absorption and metabolism of flavonoid glucosides. CBG is found predominately in the liver, but is also located in tissues such as spleen, small intestine and kidney. Through its catalytic activity, CBG is able to hydrolyze a variety of glycosides including phytoestrogens, cyanogens, and flavonols. Although its catalytic activity extends to many dietary flavonoids, CBG has increased specificity for hydrophobic aglycones such as beta-D-glucoside and beta-D-galactoside. Hydrolysis is inhibited by sodium taurocholate and glucosyl-sphingosine, both of which regulate CBG enzymatic activity. Deficiencies in CBG have been implicated in Gaucher’s disease, a lysosomal storage disease that causes a build up of fatty material in the spleen, liver, lung and kidneys.
Reactivity Human, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human GBA3/CBG
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym CBG, CBGL1, Cytosolic beta glucosidase, Cytosolic beta glucosidase like protein 1, Cytosolic beta-glucosidase, Cytosolic beta-glucosidase-like protein 1, GBA3, GBA3_HUMAN, GLUC, Glucosidase beta acid 3, Klotho related protein.
This product is for research use only, not for diagnostic or therapeutic use!

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