| No | Size | Price | Availability | |
| YRP13236-01 | 50ul | 1500.00 | In Stock |  |
| YRP13236-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2529 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles, which are reliant on adhesion molecules such as Selectins (1-3). Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking (4-6). Alpha 1,3-fucosyltransferase VII (FucT-VII) mediates the targeting of effector T cells to sites of inflammation by modifying surface ligands which are compatible to endothelial selectins (7). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human FUT7/FucT-VII |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | 3-fucosyltransferase, Alpha 1,3 fucosyltransferase, Alpha-1, Fuc-TVII, Fucosyltransferase 7, Fucosyltransferase VII, FucT VII, FucT-VII, FUT7, FUT7_HUMAN, Galactoside 3 L fucosyltransferase, Galactoside 3-L-fucosyltransferase, Selectin ligand synthase. |
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