Source: | Rabbit | Gene Id: | 158326 |
Isotype: | IgG | Swiss Prot: | |
purity: | Purified by Protein A. |
Background: |
FREM1 is a 2,179 amino acid protein that contains one C-type lectin domain, one Calx-beta domain and twelve CSPG repeats. Localized to the basement membrane of embryonic epidermal cells and secreted into extracellular space, FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. FREM1 exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 9. Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. |
Reactivity | Human, Mouse, Rat |
Tested applications | IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from human FREM1 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | BC037594, BNAR, C9orf143, C9orf145, C9orf154, D430009N09, D630008K06, FLJ25461, FRAS1-related extracellular matrix protein 1, FREM 1, FREM1, FREM1_HUMAN, Heb, MOTA, Protein QBRICK, QBRICK, RGD1306981, RP11-265B7.2, RP23-410K19.1, TILRR. |
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