| No | Size | Price | Availability | |
| YRP13041-01 | 50ul | 1500.00 | In Stock |  |
| YRP13041-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 1847 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), MKP-2, MKP-3, MKP-4, MKP-5, MKP-6, MKP-7, MKP-X, VHR, VHY, PAC1, hVH-3 (B23), hVH-5, PYST2, DUSP1, DUSP5, DUSP8, PIR1 and SKRP1. DUSP5 is a nuclear phosphoprotein that displays phosphatase activity toward several different substrates. It shows the highest relative activity toward ERK1. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
|
| Immunogen | KLH conjugated synthetic peptide derived from human DUSP5 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | Dual specicity protein phosphatase 5, Dual specicity protein phosphatase hVH 3, Dual specicity protein phosphatase hVH3, DUSP 5, DUSP, HVH 3, HVH3, Serine/threonine specic protein phosphatase, VH 3, VH1 like phosphatase 3, VH3, DUS5_HUMAN. |
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