| No | Size | Price | Availability | |
| YRP12576-01 | 50ul | 1500.00 | In Stock |  |
| YRP12576-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 8815 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Barrier-to-autointegration factor (BAF) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BAF compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BAF from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human BANF1/BAF |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | BAF, BAF_HUMAN, BANF 1, BANF1, Barrier to autointegration factor 1, Barrier to autointegration factor, Barrier-to-autointegration factor, BCRG 1, BCRG1, BCRP 1, BCRP1, Breakpoint cluster region protein 1, D14S1460, MGC111161. |
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