| No | Size | Price | Availability | |
| YRP00329-01 | 50ul | 1500.00 | In Stock |  |
| YRP00329-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 15139 |
| Isotype: | IgG | Swiss Prot: | P06684 |
| purity: | Purified by Protein A. |
| Background: |
| Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation. |
| Reactivity | Mouse |
| Tested applications | IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from mouse C5a (725-770aa) |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | C5, He, C5a, Complement C5, Hemolytic complement, Hc |
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