ARFRP1 Rabbit Polyclonal Antibody
No Size Price Availability  
YRP12519-01 50ul 1500.00 In Stock
YRP12519-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 10139
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
The ADP-ribosylation factor (ARF) protein family are structurally and functionally conserved members of the Ras superfamily of regulatory GTP-binding proteins. ARFs influence vesicle trafficking and signal transduction in eukaryotic cells and they play a central role in the maintenance of organelle integrity, assembly of coat proteins and activation of phospholipase D (PC-PLD). ARFRP1 (ADP-ribosylation factor related protein 1), also known as ARP or ARL18, is a 201 amino acid membrane-associated GTPase that localizes to the plasma membrane and the Golgi apparatus and is related to the ARF family of regulatory proteins. Expressed in a variety of tissues, ARFRP1 interacts with SYS1 and is thought to be involved in plasma membrane-related signaling events. ARFRP1 exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to a gene cluster on chromosome 20 that is commonly overexpressed in tumors, suggesting a role for ARFRP1 in carcinogenesis.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human ARFRP1
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym ADP ribosylation factor related protein 1, ARF related protein 1, ARF related protein, ARL 18, ARL18, ARP 1, ARP, ARP1, Helicase like protein NHL, MGC6837, SCG10 like protein, ARFRP_HUMAN.
This product is for research use only, not for diagnostic or therapeutic use!

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