IPMK Rabbit Polyclonal Antibody
No Size Price Availability  
YRP12390-01 50ul 1500.00 In Stock
YRP12390-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 253430
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
Inositol polyphosphate multikinase (IPMK) belongs to the inositol phosphokinase (IPK) family and is characterized as having a broad substrate specificity. However, IPMK displays a preference for inositol-1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4). IPMK is ubiquitously expressed with the highest expression in skeletal muscle, liver, placenta, lung, peripheral blood leukocytes, kidney, spleen and colon. IPMK is localized to the nucleus, where it may play a role in the regulation of calcium release from intracellular stores and has been implicated as a drug target for cancer therapies. The gene encoding IPMK maps to human chromosome 10, which contains over 800 genes. Notably, disorders linked to genes on chromosome 10 include Cowden syndrome, Cockayne syndrome and Tetrahydrobiopterin deficiency.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human IPMK
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym 6-tetrakisphosphate 5-kinase, Inositol 1, Inositol 1,3,4,6 tetrakisphosphate 5 kinase, Inositol polyphosphate multikinase, Ipmk, IPMK_HUMAN
This product is for research use only, not for diagnostic or therapeutic use!

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