| No | Size | Price | Availability | |
| YRP12358-01 | 50ul | 1500.00 | In Stock |  |
| YRP12358-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 84667 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| HES7 is a 225 amino acid transcriptional repressor protein. Localized to the nucleus, HES7 represses transcription of N box- and E box-containing promoters. HES7, along with family member HES1, is thought to cooperatively regulate somite formation in the presomitic mesoderm. HES7 may also be essential for coordinated somite segmentation by acting as a segmentation clock. HES7 contains one basic helix-loop-helix (bHLH) domain and one Orange domain. Mutations in HES7 have been found to cause spondylocostal dysostosis, an autosomal recessive disorder characterized by deformities of the chest and spine. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human HES7 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | bHLH factor Hes7, bHLHb37, Class B basic helix loop helix protein 37, Class B basic helix-loop-helix protein 37, hairy and enhancer of split 7, Hes7, HES7_HUMAN, hHes7, SCDO4, Transcription factor HES 7, Transcription factor HES-7. |
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