| No | Size | Price | Availability | |
| YRP00287-01 | 50ul | 1500.00 | In Stock |  |
| YRP00287-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 892 |
| Isotype: | IgG | Swiss Prot: | P24863 |
| purity: | Purified by Protein A. |
| Background: |
| Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human Cyclin C |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | CycC, Cyclin-C, SRB11 homolog, hSRB11, CCNC |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
