| No | Size | Price | Availability | |
| YRP12346-01 | 50ul | 1500.00 | In Stock |  |
| YRP12346-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2116 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| ER71 is a 341 amino acid member of the ETS protein family. Localized to the nucleus, ER71 contains one ETS DNA-binding domain which binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'. The gene encoding ER71 maps to human chromosome 19, which consists of around 63 million bases with over 1,400 genes, making up over 2% of human genomic DNA. Chromosome 19 is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc?receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human ETV2/ER71 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | ER71, Ets related protein 71, ETS translocation variant 2, Ets variant gene 2, Ets-related protein 71, ETSRP71, ETV2_HUMAN. |
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