ABCB11 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP8647-01 50ul 1500.00 In Stock
ARP8647-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 8647
Isotype: IgG Swiss Prot: O95342
purity: Affinity purification
Background:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.
Reactivity Human, Mouse
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 146kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen Recombinant protein of human ABCB11
Storage Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym BSEP, PGY4, SPGP, ABC16, BRIC2, PFIC2, PFIC-2
This product is for research use only, not for diagnostic or therapeutic use!

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