| No | Size | Price | Availability | |
| YRP12333-01 | 50ul | 1500.00 | In Stock |  |
| YRP12333-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 171558 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Maturation of cytotoxic T lymphocytes is mediated in part by a structure on the T cell surface known as the T cell antigen receptor (TCR) complex. The pre-TCR complex consists of pre-TCR ?¡À, pre-TCR ?2and CD3, which together help coordinate early thymocyte development. Pre-TCR ?¡À chain is a type I transmembrane glycoprotein with an extracellular region similar to the constant domain of the immunoglobulin supergene family. Notch3 transgenic mice lacking pre-TCR ?¡À inhibits tumor development. In humans, acute lymphoblastic leukemias (ALL) in remission have lower transcript levels of Notch3, HES-1 and pre-TCR ?¡À transcripts a and b relative to proliferating ALLs. The human pre-TCR ?¡À gene is expressed in immature T cells and maps to chromosome 6p |
| Reactivity | Human, Mouse |
| Tested applications | WB FC IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
FC 1:20-1:100
|
| Immunogen | KLH conjugated synthetic peptide derived from human TCR alpha |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | T cell antigen receptor alpha polypeptide, T cell receptor alpha, T cell receptor alpha locus, TCRA, TCRD, TRA, PTCRA_HUMAN. |
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