XPC Rabbit Polyclonal Antibody
No Size Price Availability  
ARP7508-01 50ul 1500.00 In Stock
ARP7508-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 7508
Isotype: IgG Swiss Prot: Q01831
purity: Affinity purification
Background:
This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
Reactivity Human
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 106kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen Recombinant protein of human XPC
Storage Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym XP3, RAD4, XPCC, p125
This product is for research use only, not for diagnostic or therapeutic use!

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