ABCC8 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP6833-01 50ul 1500.00 In Stock
ARP6833-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 6833
Isotype: IgG Swiss Prot: Q09428
purity: Affinity purification
Background:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene.
Reactivity Mouse
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 177kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen Recombinant protein of human ABCC8
Storage Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym HI, SUR, HHF1, MRP8, PHHI, SUR1, ABC36, HRINS, TNDM2, SUR1delta2
This product is for research use only, not for diagnostic or therapeutic use!

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