GRK1 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP6011-01 50ul 1500.00 In Stock
ARP6011-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 6011
Isotype: IgG Swiss Prot: Q15835
purity: Affinity purification
Background:
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.
Reactivity Human, Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 63.5kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:200
Immunogen A synthetic peptide of human GRK1
Storage Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym RK, RHOK, GPRK
This product is for research use only, not for diagnostic or therapeutic use!

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