| No | Size | Price | Availability | |
| ARP3133-01 | 50ul | 1500.00 | In Stock |  |
| ARP3133-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3133 |
| Isotype: | IgG | Swiss Prot: | P13747 |
| purity: | Affinity purification |
| Background: |
| HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 40kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | Recombinant protein of human HLA-E |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | MHC, QA1, EA1.2, EA2.1, HLA-6.2 |
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