| No | Size | Price | Availability | |
| ARP3043-01 | 50ul | 1500.00 | In Stock |  |
| ARP3043-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3043 |
| Isotype: | IgG | Swiss Prot: | P68871 |
| purity: | Affinity purification |
| Background: |
| Hemoglobin (Hgb) is coupled to four iron-binding, methene-linked tetrapyrrole rings (heme). The å (16p13.3; 5'-Ω-pseudoz-pseudo å2-pseudo å1-å2-å1-œ1-3') and ∫ (11p15.5) globin loci determine the basic hemoglobin structure. The globin portion of hemoglobin consists of two å chains and two ∫ chains arranged in pairs forming a tetramer. Each of the four globin chains covalently associates with a heme group. The bonds between å and ∫ chains are weaker than between similar globin chains, thereby forming a cleavage plane that is important for oxygen binding and release. High affinity for oxygen occurs upon relaxation of the å1-∫2 cleavage plane. When the two å1-∫2 interfaces are closely bound, hemoglobin has a low affinity for oxygen. Hb A, which contains two å chains plus two ∫ chains, comprises 97% of total circulating hemoglobin. The remaining 3% of total circulating hemoglobin is comprised of Hb A-2, which consists of two å chains plus two ∂ chains, and fetal hemoglobin (Hb F), which consists of two å chains together with two © chains. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC FC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 16kDa |
| Recommended Dilutions |
WB 1:200-1:500
IHC 1:50-1:100F
FC 1:20-1:50
|
| Immunogen | Recombinant protein of human HBB |
| Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | HBB, Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain, LVV-hemorphin-7 |
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