Source: | Rabbit | Gene Id: | 3000 |
Isotype: | IgG | Swiss Prot: | Q02846 |
purity: | Affinity purification |
Background: |
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 120kDa |
Recommended Dilutions |
WB 1:200-1:2000
|
Immunogen | A synthetic peptide of human GUCY2D |
Storage | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | LCA, CYGD, LCA1, RCD2, CORD5, CORD6, GUC2D, ROSGC, retGC, GUC1A4, RETGC-1, ROS-GC1 |
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