CDK6 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP1021-02 50ul 1500.00 In Stock
ARP1021-02 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 1021
Isotype: IgG Swiss Prot: Q00534
purity: Affinity purification
Background:
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Reactivity Human, Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 37kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:100
Immunogen Recombinant protein of human CDK6
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym PLSTIRE
This product is for research use only, not for diagnostic or therapeutic use!

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