TP53I3 Rabbit Polyclonal Antibody
| No |
Size |
Price |
Availability |
|
| ARP9540-01 |
50ul |
1500.00 |
In Stock |
 |
| ARP9540-01 |
100ul |
2000.00 |
In Stock |
|
| Source: |
Rabbit |
Gene Id: |
9540 |
| Isotype: |
IgG |
Swiss Prot: |
Q53FA7 |
| purity: |
Affinity purification |
| Background: |
| The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Reactivity |
Human, Mouse, Rat |
| Tested applications |
WB |
| Clonality |
Polyclonal Antibody |
| Calculated MW |
36 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen |
Recombinant protein of human TP53I3 |
| Storage |
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym |
PIG3 |
This product is for research use only, not for diagnostic or therapeutic use！
