COX7A2L Rabbit Polyclonal Antibody
No Size Price Availability  
ARP9167-01 50ul 1500.00 In Stock
ARP9167-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 9167
Isotype: IgG Swiss Prot: O14548
purity: Affinity purification
Background:
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.
Reactivity Human
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 13 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen Recombinant protein of human COX7A2L
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym
This product is for research use only, not for diagnostic or therapeutic use!

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