CLDN8 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP9073-01 50ul 1500.00 In Stock
ARP9073-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 9073
Isotype: IgG Swiss Prot: P56748
purity: Affinity purification
Background:
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.[provided by RefSeq, May 2010]
Reactivity Human
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 25 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen Recombinant protein of human CLDN8
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym
This product is for research use only, not for diagnostic or therapeutic use!

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