Source: | Rabbit | Gene Id: | 84676 |
Isotype: | IgG | Swiss Prot: | Q969Q1 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | 40 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:100
IF 1:50-1:100
|
Immunogen | Synthetic Peptide of human TRIM63 |
Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | IRF, SMRZ, MURF1, MURF2, RNF28 |
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