Source: | Rabbit | Gene Id: | 8370 |
Isotype: | IgG | Swiss Prot: | P62805 |
purity: | Affinity purification |
Background: |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. |
Reactivity | Human, Mouse, Rat, Other (Wide Range) |
Tested applications | WB IHC IF IP ChIP ChIPseq |
Clonality | Polyclonal Antibody |
Calculated MW | 11 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:50-1:200
ChIP 1:20-1:100
|
Immunogen | Synthetic Peptide of human H4K20me2 |
Storage | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | H4, H4/n, H4F2, H4FN, FO108, HIST2H4 |
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