TNNI2 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP7136-01 50ul 1500.00 In Stock
ARP7136-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 7136
Isotype: IgG Swiss Prot: P48788
purity: Affinity purification
Background:
This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
Reactivity Human
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 21 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:200
Immunogen Recombinant protein of human TNNI2
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym DA2B, FSSV, fsTnI, AMCD2B
This product is for research use only, not for diagnostic or therapeutic use!

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