Phospho-CCND1-T286 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP595P-01 50ul 1500.00 In Stock
ARP595P-01 100ul 2000.00 In Stock
  • Details
  • FAQs
  • Manual
Source: Rabbit Gene Id: 595
Isotype: IgG Swiss Prot: P24385
purity: Affinity purification
Background:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008]
Reactivity Human
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 34 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen Synthetic Peptide of human Phospho-CCND1-T286
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym BCL1, PRAD1, U21B31, D11S287E
This product is for research use only, not for diagnostic or therapeutic use!

backtop
QQ
service center
Contact Us