ALOXE3 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP59344-01 50ul 1500.00 In Stock
ARP59344-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 59344
Isotype: IgG Swiss Prot: Q9BYJ1
purity: Affinity purification
Background:
This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene
Reactivity Human
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 81 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen Recombinant protein of human ALOXE3
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym ARCI3, E-LOX, eLOX3, eLOX-3
This product is for research use only, not for diagnostic or therapeutic use!

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