PTN Rabbit Polyclonal Antibody
No Size Price Availability  
ARP5764-01 50ul 1500.00 In Stock
ARP5764-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5764
Isotype: IgG Swiss Prot: P21246
purity: Affinity purification
Background:
Pleiotrophin (PTN) also known as heparin-binding brain mitogen (HBBM) or heparin-binding growth factor 8 (HBGF-8) or neurite growth-promoting factor 1 (NEGF1) or heparin affinity regulatory peptide (HARP) or heparin binding growth associated molecule (HB-GAM) is a protein that in humans is encoded by the PTNgene. Pleiotrophin is an 18-kDa growth factor that has a high affinity for heparin. It is structurally related to midkine and retinoic acid induced heparin-binding protein. Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.
Reactivity Human, Mouse, Rat
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 19 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen Synthetic Peptide of human PTN
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym HARP, HBNF, HBGF8, NEGF1
This product is for research use only, not for diagnostic or therapeutic use!

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