RBFOX1 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP54715-01 50ul 1500.00 In Stock
ARP54715-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 54715
Isotype: IgG Swiss Prot: Q9NWB1
purity: Affinity purification
Background:
The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Reactivity Human
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 43 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:200
Immunogen Recombinant protein of human RBFOX1
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym 2BP1, FOX1, A2BP1, FOX-1, HRNBP1
This product is for research use only, not for diagnostic or therapeutic use!

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