FAM3B Rabbit Polyclonal Antibody
No Size Price Availability  
ARP54097-01 50ul 1500.00 In Stock
ARP54097-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 54097
Isotype: IgG Swiss Prot: P58499
purity: Affinity purification
Background:
FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome.
Reactivity Human, Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 26 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:200
Immunogen Recombinant protein of human FAM3B
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym 2-21, ORF9, PANDER, PRED44, C21orf11, C21orf76
This product is for research use only, not for diagnostic or therapeutic use!

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