PRKAG3 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP53632-01 50ul 1500.00 In Stock
ARP53632-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 53632
Isotype: IgG Swiss Prot: Q9UGI9
purity: Affinity purification
Background:
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.
Reactivity Human
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW 54 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:50-1:100
Immunogen Recombinant protein of human PRKAG3
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym AMPKG3
This product is for research use only, not for diagnostic or therapeutic use!

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