PLCG1 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP5335-01 50ul 1500.00 In Stock
ARP5335-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5335
Isotype: IgG Swiss Prot: P19174
purity: Affinity purification
Background:
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
Reactivity Human, Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 149 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:200
Immunogen Synthetic Peptide of human PLCG1
Storage Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1
This product is for research use only, not for diagnostic or therapeutic use!

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